Seattle Genetics

Research Associate II/III, Translational Sciences/Quantitative Pharmacology

Description

Summary:

The Translational Sciences department is seeking a highly motivated and creative research associate to assist with critical reagent discovery and bioanalytical assay development. This work will support the advancement of multiple antibody-drug conjugate (ADC) and immuno-oncology biotherapeutics from late-stage research into clinical development. The successful candidate will have experience in standard and exploratory bioanalytical techniques that can be used to characterize the pharmacokinetics, pharmacology, biodistribution, and/or stability of antibody-based drugs.

Responsibilities:

• Assist in the design and development of ligand binding assays, immunopurification techniques, and novel bioanalytical methods used to measure and characterize therapeutic drugs or novel drug-linker platforms in various biological matrices.
• Participate in the evaluation and implementation of these methods to characterize therapeutic drugs in in vitro and in vivo studies and models.
• Perform physical, kinetic, and functional screening and characterization of critical reagents.
• Organize/maintain hybridoma and mAb libraries. Manage DNA sequencing and perform cloning of lead critical reagent candidates.
• Analyze, summarize, and present data in group meetings and contribute to discussions.

Qualifications:

• Bachelor’s or Master’s degree in Biological Sciences or related discipline with a minimum 3 years (+BS) or 1 year (+MS) of relevant research/industry experience.
• Experience with standard immunoassays and protein characterization.
• Experience with bioanalytical principles and techniques (including assay development), hybridoma generation, and tissue culture is a plus.
• Ability to thrive in a dynamic, collaborative work environment and communicate effectively both verbally and non-verbally.
• Strong organization and multitasking skills, computer and analytical programs (Excel, Word, PowerPoint, Unifi, SoftMax Pro), and familiarity with database management.

Seattle Genetics is an equal opportunity employer. All qualified applications will receive consideration for employment without regard to race, color, religion, sex, national origin, protected veteran status, or disability status.

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Seattle Genetics

Seattle Genetics is an Equal Opportunity Employer

Submitted: 02/02/2018